New Insight in Cold Pain: Role of Ion Channels, Modulation, and Clinical Perspectives.
Identifieur interne : 001A49 ( Main/Exploration ); précédent : 001A48; suivant : 001A50New Insight in Cold Pain: Role of Ion Channels, Modulation, and Clinical Perspectives.
Auteurs : Stéphane Lolignier [France] ; Dimitra Gkika [France] ; David Andersson [Royaume-Uni] ; Enrico Leipold [Allemagne] ; Irina Vetter [Australie] ; Felix Viana [Espagne] ; Jacques Noël [France] ; Jérôme Busserolles [France]Source :
- The Journal of neuroscience : the official journal of the Society for Neuroscience [ 1529-2401 ] ; 2016.
Descripteurs français
- KwdFr :
- Animaux, Basse température, Canaux ioniques (métabolisme), Douleur (physiopathologie), Humains, Médecine factuelle, Nocicepteurs (physiologie), Ouverture et fermeture des portes des canaux ioniques (physiologie), Perception de la douleur (physiologie), Plasticité neuronale (physiologie), Thermoception (physiologie).
- MESH :
- métabolisme : Canaux ioniques.
- physiologie : Nocicepteurs, Ouverture et fermeture des portes des canaux ioniques, Perception de la douleur, Plasticité neuronale, Thermoception.
- physiopathologie : Douleur.
- Animaux, Basse température, Humains, Médecine factuelle.
English descriptors
- KwdEn :
- MESH :
- chemical , metabolism : Ion Channels.
- physiology : Ion Channel Gating, Neuronal Plasticity, Nociceptors, Pain Perception, Thermosensing.
- physiopathology : Pain.
- Animals, Cold Temperature, Evidence-Based Medicine, Humans.
Abstract
Cold temperature detection involves the process of sensory transduction in cutaneous primary sensory nerve terminals, which converts thermal stimuli into depolarizations of the membrane. This transformation into electrical signals is followed by the subsequent propagation of action potentials in cold-sensitive afferent nerve fibers. A large array of ion channels shapes this process; however, the precise contribution of specific ion channel subtypes to cold perception and cold pain remains elusive. This review aims at giving an update on our current understanding of the role played by TRPs, leak K(+) and voltage-gated Na(+) and K(+) channels in the transduction of cold by nociceptors and in cold-induced pain.
DOI: 10.1523/JNEUROSCI.2327-16.2016
PubMed: 27911746
Affiliations:
- Allemagne, Australie, Espagne, France, Royaume-Uni
- Auvergne (région administrative), Auvergne-Rhône-Alpes, Hauts-de-France, Nord-Pas-de-Calais
- Clermont-Ferrand, Lille, Villeneuve d'Ascq
- Université Lille I - Sciences et technologies
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 001628
- to stream PubMed, to step Curation: 001606
- to stream PubMed, to step Checkpoint: 001606
- to stream Ncbi, to step Merge: 003F76
- to stream Ncbi, to step Curation: 003F76
- to stream Ncbi, to step Checkpoint: 003F76
- to stream Main, to step Merge: 001A45
- to stream Main, to step Curation: 001A49
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">New Insight in Cold Pain: Role of Ion Channels, Modulation, and Clinical Perspectives.</title><author><name sortKey="Lolignier, Stephane" sort="Lolignier, Stephane" uniqKey="Lolignier S" first="Stéphane" last="Lolignier">Stéphane Lolignier</name><affiliation wicri:level="1"><nlm:affiliation>Clermont Université, Université d'Auvergne, Pharmacologie fondamentale et clinique de la douleur, 63000 Clermont-Ferrand, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Clermont Université, Université d'Auvergne, Pharmacologie fondamentale et clinique de la douleur, 63000 Clermont-Ferrand</wicri:regionArea><wicri:noRegion>63000 Clermont-Ferrand</wicri:noRegion><wicri:noRegion>63000 Clermont-Ferrand</wicri:noRegion></affiliation></author><author><name sortKey="Gkika, Dimitra" sort="Gkika, Dimitra" uniqKey="Gkika D" first="Dimitra" last="Gkika">Dimitra Gkika</name><affiliation wicri:level="4"><nlm:affiliation>Laboratoire de Physiologie cellulaire, Inserm U1003, Laboratory of Excellence, Ion Channels Science and Therapeutics, Université Lille 1, 59655 Villeneuve d'Ascq Cedex, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire de Physiologie cellulaire, Inserm U1003, Laboratory of Excellence, Ion Channels Science and Therapeutics, Université Lille 1, 59655 Villeneuve d'Ascq Cedex</wicri:regionArea><wicri:noRegion>59655 Villeneuve d'Ascq Cedex</wicri:noRegion><orgName type="university">Université Lille I - Sciences et technologies</orgName><placeName><settlement type="city">Lille</settlement><region type="region" nuts="2">Hauts-de-France</region><region type="old region" nuts="2">Nord-Pas-de-Calais</region></placeName></affiliation></author><author><name sortKey="Andersson, David" sort="Andersson, David" uniqKey="Andersson D" first="David" last="Andersson">David Andersson</name><affiliation wicri:level="1"><nlm:affiliation>King's College London, Wolfson Centre for Age-Related Diseases Wolfson Wing, SE1 1UL London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>King's College London, Wolfson Centre for Age-Related Diseases Wolfson Wing, SE1 1UL London</wicri:regionArea><wicri:noRegion>SE1 1UL London</wicri:noRegion></affiliation></author><author><name sortKey="Leipold, Enrico" sort="Leipold, Enrico" uniqKey="Leipold E" first="Enrico" last="Leipold">Enrico Leipold</name><affiliation wicri:level="1"><nlm:affiliation>Institut für Biochemie und Biophysik, D-07745 Jena, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institut für Biochemie und Biophysik, D-07745 Jena</wicri:regionArea><wicri:noRegion>07745 Jena</wicri:noRegion><wicri:noRegion>07745 Jena</wicri:noRegion><wicri:noRegion>D-07745 Jena</wicri:noRegion></affiliation></author><author><name sortKey="Vetter, Irina" sort="Vetter, Irina" uniqKey="Vetter I" first="Irina" last="Vetter">Irina Vetter</name><affiliation wicri:level="1"><nlm:affiliation>Institute for Molecular Bioscience and School of Pharmacy, University of Queensland, Brisbane, Queensland 4072, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Institute for Molecular Bioscience and School of Pharmacy, University of Queensland, Brisbane, Queensland 4072</wicri:regionArea><wicri:noRegion>Queensland 4072</wicri:noRegion></affiliation></author><author><name sortKey="Viana, Felix" sort="Viana, Felix" uniqKey="Viana F" first="Felix" last="Viana">Felix Viana</name><affiliation wicri:level="1"><nlm:affiliation>Instituto de Neurociencias de Alicante Universidad Miguel Hernandez/CSIC Avda. S. Ramón y Cajal s.n. San Juan de Alicante, 03550 Alicante, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Instituto de Neurociencias de Alicante Universidad Miguel Hernandez/CSIC Avda. S. Ramón y Cajal s.n. San Juan de Alicante, 03550 Alicante</wicri:regionArea><wicri:noRegion>03550 Alicante</wicri:noRegion></affiliation></author><author><name sortKey="Noel, Jacques" sort="Noel, Jacques" uniqKey="Noel J" first="Jacques" last="Noël">Jacques Noël</name><affiliation wicri:level="1"><nlm:affiliation>Université Côte d'Azur, CNRS UMR 7275, Institut de Pharmacologie Moléculaire et Cellulaire, France, and jerome.busserolles@udamail.fr jnoel@unice.fr.</nlm:affiliation><country wicri:rule="url">France</country><wicri:regionArea>Université Côte d'Azur, CNRS UMR 7275, Institut de Pharmacologie Moléculaire et Cellulaire, France</wicri:regionArea><wicri:noRegion>France</wicri:noRegion><wicri:noRegion>France</wicri:noRegion></affiliation></author><author><name sortKey="Busserolles, Jerome" sort="Busserolles, Jerome" uniqKey="Busserolles J" first="Jérôme" last="Busserolles">Jérôme Busserolles</name><affiliation wicri:level="1"><nlm:affiliation>Clermont Université, Université d'Auvergne, Pharmacologie fondamentale et clinique de la douleur, 63000 Clermont-Ferrand, France, jerome.busserolles@udamail.fr jnoel@unice.fr.</nlm:affiliation><country wicri:rule="url">France</country><wicri:regionArea>Clermont Université, Université d'Auvergne, Pharmacologie fondamentale et clinique de la douleur, 63000 Clermont-Ferrand, France</wicri:regionArea><wicri:noRegion>France</wicri:noRegion><wicri:noRegion>France</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2016">2016</date><idno type="RBID">pubmed:27911746</idno><idno type="pmid">27911746</idno><idno type="doi">10.1523/JNEUROSCI.2327-16.2016</idno><idno type="wicri:Area/PubMed/Corpus">001628</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001628</idno><idno type="wicri:Area/PubMed/Curation">001606</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001606</idno><idno type="wicri:Area/PubMed/Checkpoint">001606</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001606</idno><idno type="wicri:Area/Ncbi/Merge">003F76</idno><idno type="wicri:Area/Ncbi/Curation">003F76</idno><idno type="wicri:Area/Ncbi/Checkpoint">003F76</idno><idno type="wicri:Area/Main/Merge">001A45</idno><idno type="wicri:Area/Main/Curation">001A49</idno><idno type="wicri:Area/Main/Exploration">001A49</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">New Insight in Cold Pain: Role of Ion Channels, Modulation, and Clinical Perspectives.</title><author><name sortKey="Lolignier, Stephane" sort="Lolignier, Stephane" uniqKey="Lolignier S" first="Stéphane" last="Lolignier">Stéphane Lolignier</name><affiliation wicri:level="3"><nlm:affiliation>Clermont Université, Université d'Auvergne, Pharmacologie fondamentale et clinique de la douleur, 63000 Clermont-Ferrand, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Clermont Université, Université d'Auvergne, Pharmacologie fondamentale et clinique de la douleur, 63000 Clermont-Ferrand</wicri:regionArea><placeName><region type="region" nuts="2">Auvergne-Rhône-Alpes</region><region type="old region" nuts="2">Auvergne (région administrative)</region><settlement type="city">Clermont-Ferrand</settlement></placeName></affiliation></author><author><name sortKey="Gkika, Dimitra" sort="Gkika, Dimitra" uniqKey="Gkika D" first="Dimitra" last="Gkika">Dimitra Gkika</name><affiliation wicri:level="4"><nlm:affiliation>Laboratoire de Physiologie cellulaire, Inserm U1003, Laboratory of Excellence, Ion Channels Science and Therapeutics, Université Lille 1, 59655 Villeneuve d'Ascq Cedex, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire de Physiologie cellulaire, Inserm U1003, Laboratory of Excellence, Ion Channels Science and Therapeutics, Université Lille 1, 59655 Villeneuve d'Ascq Cedex</wicri:regionArea><placeName><region type="region" nuts="2">Hauts-de-France</region><region type="old region" nuts="2">Nord-Pas-de-Calais</region><settlement type="city">Villeneuve d'Ascq</settlement><settlement type="city">Lille</settlement></placeName><orgName type="university">Université Lille I - Sciences et technologies</orgName></affiliation></author><author><name sortKey="Andersson, David" sort="Andersson, David" uniqKey="Andersson D" first="David" last="Andersson">David Andersson</name><affiliation wicri:level="1"><nlm:affiliation>King's College London, Wolfson Centre for Age-Related Diseases Wolfson Wing, SE1 1UL London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>King's College London, Wolfson Centre for Age-Related Diseases Wolfson Wing, SE1 1UL London</wicri:regionArea><wicri:noRegion>SE1 1UL London</wicri:noRegion></affiliation></author><author><name sortKey="Leipold, Enrico" sort="Leipold, Enrico" uniqKey="Leipold E" first="Enrico" last="Leipold">Enrico Leipold</name><affiliation wicri:level="1"><nlm:affiliation>Institut für Biochemie und Biophysik, D-07745 Jena, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institut für Biochemie und Biophysik, D-07745 Jena</wicri:regionArea><wicri:noRegion>07745 Jena</wicri:noRegion><wicri:noRegion>07745 Jena</wicri:noRegion><wicri:noRegion>D-07745 Jena</wicri:noRegion></affiliation></author><author><name sortKey="Vetter, Irina" sort="Vetter, Irina" uniqKey="Vetter I" first="Irina" last="Vetter">Irina Vetter</name><affiliation wicri:level="1"><nlm:affiliation>Institute for Molecular Bioscience and School of Pharmacy, University of Queensland, Brisbane, Queensland 4072, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Institute for Molecular Bioscience and School of Pharmacy, University of Queensland, Brisbane, Queensland 4072</wicri:regionArea><wicri:noRegion>Queensland 4072</wicri:noRegion></affiliation></author><author><name sortKey="Viana, Felix" sort="Viana, Felix" uniqKey="Viana F" first="Felix" last="Viana">Felix Viana</name><affiliation wicri:level="1"><nlm:affiliation>Instituto de Neurociencias de Alicante Universidad Miguel Hernandez/CSIC Avda. S. Ramón y Cajal s.n. San Juan de Alicante, 03550 Alicante, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Instituto de Neurociencias de Alicante Universidad Miguel Hernandez/CSIC Avda. S. Ramón y Cajal s.n. San Juan de Alicante, 03550 Alicante</wicri:regionArea><wicri:noRegion>03550 Alicante</wicri:noRegion></affiliation></author><author><name sortKey="Noel, Jacques" sort="Noel, Jacques" uniqKey="Noel J" first="Jacques" last="Noël">Jacques Noël</name><affiliation wicri:level="1"><nlm:affiliation>Université Côte d'Azur, CNRS UMR 7275, Institut de Pharmacologie Moléculaire et Cellulaire, France, and jerome.busserolles@udamail.fr jnoel@unice.fr.</nlm:affiliation><country wicri:rule="url">France</country><wicri:regionArea>Université Côte d'Azur, CNRS UMR 7275, Institut de Pharmacologie Moléculaire et Cellulaire, France</wicri:regionArea><wicri:noRegion>France</wicri:noRegion><wicri:noRegion>France</wicri:noRegion></affiliation></author><author><name sortKey="Busserolles, Jerome" sort="Busserolles, Jerome" uniqKey="Busserolles J" first="Jérôme" last="Busserolles">Jérôme Busserolles</name><affiliation wicri:level="1"><nlm:affiliation>Clermont Université, Université d'Auvergne, Pharmacologie fondamentale et clinique de la douleur, 63000 Clermont-Ferrand, France, jerome.busserolles@udamail.fr jnoel@unice.fr.</nlm:affiliation><country wicri:rule="url">France</country><wicri:regionArea>Clermont Université, Université d'Auvergne, Pharmacologie fondamentale et clinique de la douleur, 63000 Clermont-Ferrand, France</wicri:regionArea><wicri:noRegion>France</wicri:noRegion><wicri:noRegion>France</wicri:noRegion></affiliation></author></analytic><series><title level="j">The Journal of neuroscience : the official journal of the Society for Neuroscience</title><idno type="eISSN">1529-2401</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Cold Temperature</term><term>Evidence-Based Medicine</term><term>Humans</term><term>Ion Channel Gating (physiology)</term><term>Ion Channels (metabolism)</term><term>Neuronal Plasticity (physiology)</term><term>Nociceptors (physiology)</term><term>Pain (physiopathology)</term><term>Pain Perception (physiology)</term><term>Thermosensing (physiology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Basse température</term><term>Canaux ioniques (métabolisme)</term><term>Douleur (physiopathologie)</term><term>Humains</term><term>Médecine factuelle</term><term>Nocicepteurs (physiologie)</term><term>Ouverture et fermeture des portes des canaux ioniques (physiologie)</term><term>Perception de la douleur (physiologie)</term><term>Plasticité neuronale (physiologie)</term><term>Thermoception (physiologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Ion Channels</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Canaux ioniques</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Nocicepteurs</term><term>Ouverture et fermeture des portes des canaux ioniques</term><term>Perception de la douleur</term><term>Plasticité neuronale</term><term>Thermoception</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Ion Channel Gating</term><term>Neuronal Plasticity</term><term>Nociceptors</term><term>Pain Perception</term><term>Thermosensing</term></keywords><keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr"><term>Douleur</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Pain</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Cold Temperature</term><term>Evidence-Based Medicine</term><term>Humans</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Basse température</term><term>Humains</term><term>Médecine factuelle</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Cold temperature detection involves the process of sensory transduction in cutaneous primary sensory nerve terminals, which converts thermal stimuli into depolarizations of the membrane. This transformation into electrical signals is followed by the subsequent propagation of action potentials in cold-sensitive afferent nerve fibers. A large array of ion channels shapes this process; however, the precise contribution of specific ion channel subtypes to cold perception and cold pain remains elusive. This review aims at giving an update on our current understanding of the role played by TRPs, leak K(+) and voltage-gated Na(+) and K(+) channels in the transduction of cold by nociceptors and in cold-induced pain.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Espagne</li><li>France</li><li>Royaume-Uni</li></country><region><li>Auvergne (région administrative)</li><li>Auvergne-Rhône-Alpes</li><li>Hauts-de-France</li><li>Nord-Pas-de-Calais</li></region><settlement><li>Clermont-Ferrand</li><li>Lille</li><li>Villeneuve d'Ascq</li></settlement><orgName><li>Université Lille I - Sciences et technologies</li></orgName></list><tree><country name="France"><region name="Auvergne-Rhône-Alpes"><name sortKey="Lolignier, Stephane" sort="Lolignier, Stephane" uniqKey="Lolignier S" first="Stéphane" last="Lolignier">Stéphane Lolignier</name></region><name sortKey="Busserolles, Jerome" sort="Busserolles, Jerome" uniqKey="Busserolles J" first="Jérôme" last="Busserolles">Jérôme Busserolles</name><name sortKey="Gkika, Dimitra" sort="Gkika, Dimitra" uniqKey="Gkika D" first="Dimitra" last="Gkika">Dimitra Gkika</name><name sortKey="Noel, Jacques" sort="Noel, Jacques" uniqKey="Noel J" first="Jacques" last="Noël">Jacques Noël</name></country><country name="Royaume-Uni"><noRegion><name sortKey="Andersson, David" sort="Andersson, David" uniqKey="Andersson D" first="David" last="Andersson">David Andersson</name></noRegion></country><country name="Allemagne"><noRegion><name sortKey="Leipold, Enrico" sort="Leipold, Enrico" uniqKey="Leipold E" first="Enrico" last="Leipold">Enrico Leipold</name></noRegion></country><country name="Australie"><noRegion><name sortKey="Vetter, Irina" sort="Vetter, Irina" uniqKey="Vetter I" first="Irina" last="Vetter">Irina Vetter</name></noRegion></country><country name="Espagne"><noRegion><name sortKey="Viana, Felix" sort="Viana, Felix" uniqKey="Viana F" first="Felix" last="Viana">Felix Viana</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001A49 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001A49 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Asie
|area= AustralieFrV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:27911746
|texte= New Insight in Cold Pain: Role of Ion Channels, Modulation, and Clinical Perspectives.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:27911746" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a AustralieFrV1
| This area was generated with Dilib version V0.6.33. |  |